The information on this website is intended to provide scientific information about Alkermes products and areas of therapeutic interest. Information may include data on investigational uses of approved or unapproved drugs for which safety and effectiveness have not been established. There is no guarantee that such uses will receive health authority approval and Alkermes does not recommend or suggest use of its medicines in a manner inconsistent with approved labeling.

This section includes selected Alkermes abstracts, posters or oral presentations, which have been accepted for congress presentations in the last 2 years. The content contained in this section is subject to congress copyright permissions.

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PLEASE NOTE: Materials will be available on a rolling basis after individual embargoes are lifted. Audio abstracts are generated using text-to-speech software and contain an audio version of the abstract that was submitted and accepted as part of the official conference materials.
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SLEEP (Annual Meeting of the Associated Professional Sleep Societies)
June 7th – 11th 2025
Sleep-wake disorders
POSTER
Evaluation of Cardiac Safety Profile of ALKS 2680 in Healthy Subjects: Concentration-QTc Relationship of ALKS 2680
AUTHOR(S)

Jahnavi Kharidia,1 Borje Darpo,2 Sergey Yagoda,1 Alexandra Lovett,1 Hongqi Xue,2 Hailu Chen,1 Bhaskar Rege,1 Ishani Landry1

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Sleep-wake disorders
Sleep-wake disorders
POSTER
Diagnosis Journey, Symptoms, and Burden of Idiopathic Hypersomnia: Patient Perspectives from Qualitative Interviews
AUTHOR(S)

Michael J. Doane,1 Meaghan O’Connor,2 Miranda Lauher-Charest,2 Laura Tesler Waldman,2 and Wilbur P. Williams, III1

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Sleep-wake disorders
Sleep-wake disorders
POSTER
Effects of the Orexin 2 Receptor Agonist ALKS 2680 on qEEG in Patients With Narcolepsy and Idiopathic Hypersomnia
AUTHOR(S)

Meera Modi,1 Brendon Yee,2 Julia Chapman,2 Angela D’Rozario,2 Roman Rosipal,3 Leonardo Jose Trejo,3 G.S.F. Ruigt,3 Ron Grunstein,2 Bhaskar Rege,1 Daniel G. Smith1

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Sleep-wake disorders
Sleep-wake disorders
POSTER
The Orexin 2 Receptor Agonist ALKS 2680 in Patients with Narcolepsy or Idiopathic Hypersomnia: A Phase 1b Study
AUTHOR(S)

Ron Grunstein,1 Brendon Yee,1 Julia Chapman,1 Jian Eu Tai,1 Sheila Sivam,1 Craig Hopkinson,2 Jandira Ramos,2 Derek Matthies,2 Shifang Liu,2 Sergey Yagoda,2 Bhaskar Rege2

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Sleep-wake disorders
Sleep-wake disorders
POSTER
Evaluation of the Novel Orexin 2 Receptor Agonist ALKS 2680 on Measures of Arousal Circuit Activation in Rodents
AUTHOR(S)

Julie M. Brooks,1 Angelica M. Patino,1 Corey B. Puryear,1 Laura A. Tan,1 Brian Raymer1

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Sleep-wake disorders
Sleep-wake disorders
PRESENTATION
Effects of the Orexin 2 Receptor Agonist ALKS 2680 on qEEG in Patients with Narcolepsy and Idiopathic Hypersomnia
AUTHOR(S)

Presented by Julia Chapman

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Sleep-wake disorders