The information on this website is intended to provide scientific information about Alkermes products and areas of therapeutic interest. Information may include data on investigational uses of approved or unapproved drugs for which safety and effectiveness have not been established. There is no guarantee that such uses will receive health authority approval and Alkermes does not recommend or suggest use of its medicines in a manner inconsistent with approved labeling.

This section includes selected Alkermes abstracts, posters or oral presentations, which have been accepted for congress presentations in the last 2 years. The content contained in this section is subject to congress copyright permissions.

SLEEP 2026
SLEEP (Annual Meeting of the Associated Professional Sleep Societies)
June 14th – 17th 2026, Baltimore, MD
Explore materials from this congress
PLEASE NOTE: Materials will be available on a rolling basis after individual embargoes are lifted. Audio abstracts are generated using text-to-speech software and contain an audio version of the abstract that was submitted and accepted as part of the official conference materials.
Sleep-wake disorders
POSTER
Improvements in Quality of Life in Patients With Narcolepsy Type 1 Treated With the Orexin 2 Receptor Agonist Alixorexton
AUTHOR(S)

Gert Jan Lammers,1,2 Yves Dauvilliers,3 Ronald R. Grunstein,4,5 Emmanuel Mignot,6 David T. Plante,7 Erik Buntinx,8 Rafael del Río Villegas,9,10 Hailu Chen,11 Craig Hopkinson,11 Bhaskar Rege,11 Julie Himes,11 Michael J. Doane,11 Giuseppe Plazzi12,13 

View poster
Sleep-wake disorders
Sleep-wake disorders
PRESENTATION
Vibrance-2: A Randomized Phase 2 Study Evaluating Efficacy and Safety of the Orexin 2 Receptor Agonist Alixorexton in Patients With Narcolepsy Type 2
AUTHOR(S)

Richard K. Bogan,1 Giuseppe Plazzi,2,3 Emmanuel Mignot,4 Rafael del Río Villegas,5,6 Bruce Corser,7 Brendon J. Yee,8 Diego García-Borreguero,9 Chad Ruoff,10 David T. Plante,11 Hailu Chen,12 Alexandra Lovett,12 Michael J. Doane,12 Craig Hopkinson,12 Bhaskar Rege,12 Julie Himes12

View presentation
Sleep-wake disorders
Sleep-wake disorders
POSTER
Oxybate Treatment Experience and Preferences of People With Idiopathic Hypersomnia
AUTHOR(S)

John C. Carter, MD1,2; Anne Marie Morse, DO3; Michael J. Thorpy, MD4; Bruce C. Corser, MD5; Sally Ibrahim, MD1,6; Maria Picone7; Angeni Cordova, MPH7; Lauren Dougherty7; Jacqueline Brooks, MBBCh, MRCPsych8; Jennifer Gudeman, PharmD9,a 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Polysomnographic Findings in Pediatric Patients With Narcolepsy Type 1 and Narcolepsy Type 2: A Retrospective Review
AUTHOR(S)

Sally Ibrahim, MD1,2; Kiran Maski, MD, MPH3; Anne Marie Morse, DO4; Rakesh Bhattacharjee, MD5; Judith Owens, MD3; Luis E. Ortiz, MD6; Gary Feldman, MD7; Narong Simakajornboon, MD8; Joshua Henderson, BA9; Jennifer Gudeman, PharmD10,a; Brian Abaluck, MD11; Femida H. Gwadry-Sridhar, RPh, PhD9 
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Impact of Economic Status Across Race and Ethnicity on Narcolepsy Treatment Access: A Claims Database Analysis
AUTHOR(S)

Rakesh Bhattacharjee, MD1; Alec B. Platt, MD, MSCE2; Heidy Merius, DNP3,4; Omavi Bailey, MD, MPH5; Jennifer Gudeman, PharmD6,a; Johanna Hertel, PhD7; Brian Abaluck, MD7

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Treatment Access for Narcolepsy Across Patient Demographic Characteristics: A Claims Database Analysis
AUTHOR(S)

Alec B. Platt, MD, MSCE1; Rakesh Bhattacharjee, MD2; Maggie Lavender, MSN, RN, FNP-C3,4; Amber Burns, PA-C5; Jennifer Gudeman, PharmD6,a; Johanna Hertel, PhD7; Brian Abaluck, MD7
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Improvement in Sleepiness With Once-Nightly Sodium Oxybate in People With Narcolepsy Type 1 and Narcolepsy Type 2: A Specialty Pharmacy Data Analysis
AUTHOR(S)

Sarah Meskill, MD1; Laura B. Herpel, MD2,3; Michael J. Thorpy, MD4; Chad M. Ruoff, MD5; Diana Carino, PharmD, CSP, AAHIVP6; Erin Buysman, MS7; Michelle Vu, PharmD, MPH7; Brian Abaluck, MD8; Jennifer Gudeman, PharmD9,a
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Oxybate Treatment Patterns in Patients With Narcolepsy: Cohort Data From Mayo Clinic and Duke Health
AUTHOR(S)

Melissa C. Lipford, MD1; Marjorie Soltis, MD2; Allison Smither, PhD3,a; Jennifer Gudeman, PharmD4,a; Lois E. Krahn, MD5

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Sleepiness Improvement With Once-Nightly Sodium Oxybate in Patients With and Without Prior Twice-Nightly Oxybate Use: Specialty Pharmacy Data Analysis
AUTHOR(S)

Laura B. Herpel, MD1,2; Michael J. Thorpy, MD3; Sarah Meskill, MD4; Chad M. Ruoff, MD5; Erin Buysman, MS6; Diana Carino, PharmD, CSP, AAHIVP7; Michelle Vu, PharmD, MPH6; Brian Abaluck, MD8; Jennifer Gudeman, PharmD9,a
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Brilliance NT1: Study Design and Methods for Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating Alixorexton in Patients With Narcolepsy Type 1
AUTHOR(S)

Giuseppe Plazzi,1,2 Emmanuel Mignot,3 Richard K. Bogan,4 Ronald R. Grunstein,5,6 Gert Jan Lammers,7,8 David T. Plante,9 Rafael del Río Villegas,10,11 Hailu Chen,12 Bikram Kabir,12 Juan Chavez,12 Bhaskar Rege,12 Craig Hopkinson,12 Julie Himes,12 Yves Dauvilliers13
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Impact of Sex and Race on Treatment of Narcolepsy: A Claims Database Analysis
AUTHOR(S)

Rakesh Bhattacharjee, MD1; Alec B. Platt, MD, MSCE2; Cecile Martin, FNP-BC, MS, RN3,4; Jennifer Gudeman, PharmD5,a; Johanna Hertel, PhD6; Brian Abaluck, MD6
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Nighttime Symptom Experience and Treatment Challenges: Perspectives From People With Narcolepsy
AUTHOR(S)

Luis E. Ortiz, MD1; Maggie Lavender, MSN, RN, FNP-C2,3; Anne Marie Morse, DO4; Beth Schneider, BA5; Matthew Horsnell, BS6; Dan Liss7; Shawn Kuczenski8; Jennifer Gudeman, PharmD9,a

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Real-World Experience of Once-Nightly Sodium Oxybate Treatment in People With Narcolepsy: Final Results From REFRESH
AUTHOR(S)

Sarah D. Meskill, MD1; Gerard Meskill, MD1; Asim Roy, MD2; Adrian Santamaria, MD3; Robyn Porpiglio, FNP-C4; Oktai Mamedov, MD5; Sally Ibrahim, MD6,7; Omavi Bailey, MD8; Richard K. Bogan, MD9,10; Laura B. Herpel, MD10,11; Matthew Davis, MD12; Jeremy D. McConnell, MD13; Gretchen S. Richards, MS14; Brian Abaluck, MD14; Jennifer Gudeman, PharmD15,a
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
REVITALYZ: A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Withdrawal Trial of Extended-Release Sodium Oxybate for Idiopathic Hypersomnia
AUTHOR(S)

Richard K. Bogan, MD, FCCP, FAASM1,2; John Harsh, PhD3; Sally Ibrahim, MD4,5; John C. Carter, MD5,6; Anne Marie Morse, DO7; Bruce C. Corser, MD8; Thomas Stern, MD9; Jacqueline Brooks, MBBCh, MRCPsych10; Brian Abaluck, MD10; Gretchen S. Richards, MS10
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Brilliance NT2: Study Design and Methods for a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Alixorexton in Patients With Narcolepsy Type 2
AUTHOR(S)

Richard K. Bogan,1 Emmanuel Mignot,2 Yves Dauvilliers,3 Ronald R. Grunstein,4,5 Gert Jan Lammers,6,7 David T. Plante,8 Rafael del Río Villegas,9,10 Feng Miao,11 Bikram Kabir,11 Juan Chavez,11 Bhaskar Rege,11 Craig Hopkinson,11 Julie Himes,11 Giuseppe Plazzi12,13 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Demographic and Clinical Characteristics of People Receiving Once-Nightly Sodium Oxybate Treatment: A Specialty Pharmacy Data Analysis
AUTHOR(S)

Chad M. Ruoff, MD1; Michael J. Thorpy, MD2; Laura B. Herpel, MD3,4; Sarah Meskill, MD5; Michelle Vu, PharmD, MPH6; Erin Buysman, MS6; Diana Carino, PharmD, CSP, AAHIVP7; Brian Abaluck, MD8; Jennifer Gudeman, PharmD9,a
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Risk Evaluation and Mitigation Strategies: From Burden to Benefit
AUTHOR(S)

Lindsay M. McCullough, MD1; Craig Chepke, MD2; Richard K. Bogan, MD3,4; Martha Curtin, MSPA, PA-C5; Diana Anderson, DMS, PA-C6; Jennifer Gudeman, PharmD7,a; Marla Scarola, MS6; Tracy Gentile, BA8; Danielle Burroughs, RPh6
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Safety and Efficacy of the Orexin 2 Receptor Agonist Alixorexton in Patients with Narcolepsy Type 1: The Phase 2 Vibrance-1 Study
AUTHOR(S)

Giuseppe Plazzi,1,2 Ronald R. Grunstein,3,4 Emmanuel Mignot,5 Gert J. Lammers,6,7 David T. Plante,8 Erik Buntinx,9 Rafael del Río Víllegas,10,11 Hailu Chen,12 Alexandra Lovett,12 Craig Hopkinson,12 Bhaskar Rege,12 Julie Himes,12 Yves Dauvilliers13
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Drug Class Utilization and Age-Related Trends in Narcolepsy and Idiopathic Hypersomnia: A Claims Database Analysis
AUTHOR(S)

Rakesh Bhattacharjee, MD1; Michael J. Thorpy, MD2; Sarah D. Meskill, MD3; Murad C. Assaad, MD4; Anne Marie Morse, DO5; Jennifer Gudeman, PharmD6,a; Brian Abaluck, MD7
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Real-World Experience and Impact of Fatigue in Narcolepsy and Idiopathic Hypersomnia: Survey Results from the ASPIRE Study
AUTHOR(S)

Michael J. Doane,1 Gretchen Murphy,1 Jane Lazar Tucker,2 Kristen McCausland,2 Claire Wylds-Wright,3,4 Lindsay Jesteadt3,4 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Alixorexton Improved Patient-Reported Disease Severity, Cognitive Functioning, and Fatigue in Patients with Narcolepsy Type 1 in the Vibrance-1 Study
AUTHOR(S)

Yves Dauvilliers,1 Ronald R. Grunstein,2,3 Emmanuel Mignot,4 Gert J. Lammers,5,6 David T. Plante,7 Erik Buntinx,8 Rafael del Río Víllegas,9,10 Hailu Chen,11 Craig Hopkinson,11 Bhaskar Rege,11 Julie Himes,11 Michael J. Doane,11 Giuseppe Plazzi12,13
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Demographics and Disease Characteristics Among Pediatric Patients With Narcolepsy
AUTHOR(S)

Kiran Maski, MD, MPH1; Anne Marie Morse, DO2; Sally Ibrahim, MD3,4; Rakesh Bhattacharjee, MD5; Judith Owens, MD1; Luis E. Ortiz, MD6; Gary Feldman, MD7; Narong Simakajornboon, MD8; Joshua Henderson, BA9; Jennifer Gudeman, PharmD10,a; Brian Abaluck, MD11; Femida H. Gwadry-Sridhar, RPh, PhD9 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Demographics and Comorbidities of Patients With Narcolepsy: A Propensity Score–Matched Cohort Study
AUTHOR(S)

Marjorie Soltis, MD1; Melissa C. Lipford, MD2; Allison Smither, PhD3,a; Jennifer Gudeman, PharmD4,a
 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Real-World Experience and Impact of Cognitive Impairment in Narcolepsy and Idiopathic Hypersomnia: Survey Results from the ASPIRE Study
AUTHOR(S)

Michael J. Doane,1 Gretchen Murphy,1 Jane Lazar Tucker,2 Kristen McCausland,2 Lindsay Jesteadt,3,4 Claire Wylds-Wright3,4 

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Relative Prevalence of Narcolepsy Type 1, Narcolepsy Type 2, and Idiopathic Hypersomnia: A Claims Database Analysis
AUTHOR(S)

Rakesh Bhattacharjee, MD1; Michael J. Thorpy, MD2; Sarah D. Meskill, MD3; Murad C. Assaad, MD4; Anne Marie Morse, DO5; Jennifer Gudeman, PharmD6,a; Brian Abaluck, MD7

View poster
Sleep-wake disorders
Sleep-wake disorders
POSTER
Once-Nightly Sodium Oxybate Improves Symptoms in People With Narcolepsy: Final Results From the Real-World REFRESH Study
AUTHOR(S)

Sarah D. Meskill, MD1; Gerard Meskill, MD1; Asim Roy, MD2; Adrian Santamaria, MD3; Robyn Porpiglio, FNP-C4; Oktai Mamedov, MD5; Sally Ibrahim, MD6,7; Omavi Bailey, MD8; Richard K. Bogan, MD9,10; Laura B. Herpel, MD10,11; Matthew Davis, MD12; Jeremy D. McConnell, MD13; Gretchen S. Richards, MS14; Brian Abaluck, MD14; Jennifer Gudeman, PharmD15,a
 

View poster
Sleep-wake disorders