The information on this website is intended to provide scientific information about Alkermes products and areas of therapeutic interest. Information may include data on investigational uses of approved or unapproved drugs for which safety and effectiveness have not been established. There is no guarantee that such uses will receive health authority approval and Alkermes does not recommend or suggest use of its medicines in a manner inconsistent with approved labeling.

Studies designed, executed, and funded by an Alkermes company.

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Jul 2018
Population Pharmacokinetic Analysis and Model-Based Simulations of Aripiprazole for a 1-Day Initiation Regimen for the Long-Acting Antipsychotic Aripiprazole Lauroxil
European Journal of Drug Metabolism and Pharmacokinetics
AUTHOR(S)
Hard ML, Wehr AY, Sadler BM, Mills RJ, von Moltke L
Jul 2018
Extended-release naltrexone (XR-NTX) for opioid use disorder in clinical practice: Vivitrol's Cost and Treatment Outcomes Registry
Addiction
AUTHOR(S)
Saxon AJ, Akerman SC, Liu CC, Sullivan MA, Silverman BL, Vocci FJ
Jul 2018
Effect of aripiprazole lauroxil in patients with acute schizophrenia as assessed by the positive and negative syndrome scale - supportive analyses from a phase 3 study
CNS Spectrums
AUTHOR(S)

Citrome L, Risinger R, Cutler AJ, Du Y, Zummo J, Nasrallah HA, Silverman BL

May 2018
Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial
Drug and Alcohol Dependence
AUTHOR(S)
Bisaga A, Mannelli P, Yu M, Nangia N, Graham CE, Tompkins DA, Kosten TR, Akerman SC, Silverman BL, Sullivan MA
Apr 2018
A randomized, double-blind, placebo-controlled proof of concept study to evaluate samidorphan in the prevention of olanzapine-induced weight gain in healthy volunteers
Schizophrenia Research
AUTHOR(S)

Silverman BL, Martin W, Memisoglu A, DiPetrillo L, Correll CU, Kane JM

Mar 2018
Efficacy and safety of aripiprazole lauroxil once-monthly versus aripiprazole once-monthly long-acting injectable formulations in patients with acute symptoms of schizophrenia: an indirect comparison of two double-blind placebo-controlled studies
Current Medical Research and Opinion
AUTHOR(S)
Cameron C, Zummo J, Desai D, Drake C, Hutton B, Kotb A, Weiden PJ
Mar 2018
Antagonists in the medical management of opioid use disorders: historical and existing treatment strategies
The American Journal on Addictions
AUTHOR(S)

Bisaga A, Mannelli P, Sullivan MA, Vosburg SK, Compton P, Woody GE, Kosten TR

Dec 2017
Efficacy and safety of aripiprazole lauroxil in schizophrenic patients presenting with severe psychotic symptoms during an acute exacerbation
Schizophrenia Research
AUTHOR(S)
Potkin SG, Risinger R, Du Y, Zummo J, Bose A, Silverman B, Stankovic S, Ehrich E
Aug 2017
Durability of Therapeutic Response With Long-Term Aripiprazole Lauroxil Treatment Following Successful Resolution of an Acute Episode of Schizophrenia
The Journal of Clinical Psychiatry
AUTHOR(S)
McEvoy JP, Risinger R, Mykhnyak S, Du Y, Liu CC, Stanford AD, Weiden PJ
Jul 2017
Metabolic and Endocrine Profiles During 1-Year Treatment of Outpatients with Schizophrenia with Aripiprazole Lauroxil
Psychopharmacology Bulletin
AUTHOR(S)
Nasrallah HA, Aquila R, Stanford AD, Jamal HH, Weiden PJ, Risinger R